The queue file specified in the QUEUE line of the A-Shell configuration file could not be opened. Full read/write access permission is required by all users of A-Shell both to the directory in which this file resides, and to the file once it is created. Note that in addition to the queue file (normally qflock.sys) there is also a file called jobtbl.sys which is created and managed in parallel with qflock.sys. See notes for Cannot create instance above.