Under AMOS, INMEMO uses an internal file-locking scheme based on semaphores which does not conflict with any known or imaginable locking schemes (such as FLOCK, XLOCK, and LOKSER). If your memo file is controlled by LOKSER, then you must open it with the random'forced option to have multi-user access to the memo pad.
Under the C versions, the standard OS locking mechanism for each platform is used.